Some drugs and medications have side effects that worsen acid reflux

Here is my list of other drugs which may cause acid reflux or contribute to the severity of symptoms for those who already have this condition. This list is by no means complete, plus new medicines come on the market all the time.

Calcium Channel Blockers (High blood pressure and heart problems)

Includes Cardizem®, Dilacor-XR®, Norvasc®, Procardia® and Vascor®.

Nitrates (Angina)

Includes Nitrogard®, Nitrostat®, Nitroglyn E-R® and Sorbitrate®.

Beta-2 agonists (Inhalation – bronchodilators, asthma)

Includes Alupent®, Bronkaid Mist®, Primatene Mist®, Proventil®: and Ventolin®.

Theophylline (Oral – bronchodilators, asthma)

Includes Aerolate Sr®, Choledyl®, Respbid®, Slo-Bid Gyrocaps®, Theobid Duracaps® and Theo-Dur®.

Diazepam (Anxiety disorders, seizures)

Includes Librium®, Paxipam®, Valium®, and Xanax®.

Opioid analgesics (Prescription pain killers)

Includes morphine, oxycondone (including Oxycontin®) and synthetic opioid narcotics.

Tricyclic (psychotherapeutic agents, anti-depressants)

Includes Anafranil®, Elavil®, Norpramin® and Pamelor®.

Alendronate (osteoporosis)



Anticholinergic medications, used to treat Parkinson’s disease, muscle spasms in the bladder and intestines and some eye problems. They are also found in some cold medicines.

Certain hormones such as Progesterone®, a hormone found in birth control pills.

The group of drugs known as Nsaids are on a page by themselves, follow the link for more about them.

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